Monday, January 20, 2014

GRAS

"GRAS" is an acronym for the phrase Generally Recognized ASafe. Under sections 201(s) and 409 of the Federal Food, Drug, and Cosmetic Act (the Act), any substance that is intentionally added to food is a food additive, that is subject to premarket review and approval by FDA, unless the substance is generally recognized, among qualified experts, as having been adequately shown to be safe under the conditions of its intended use, or unless the use of the substance is otherwise excluded from the definition of a food additive.There are two types of approved color additives - dyes and lakes. Dyes are water-soluble and usually come in the form of powders, granules, or liquids. Lakes are not water-soluble. They are found in products containing fats and oils.

In 1900, many foods available in the U.S. were artificially colored. However, not all of the coloring agents were harmless and some were being used to hide inferior or defective foods. A careful assessment of the chemicals used for coloring foods at the time found many blatantly poisonous materials such as lead, arsenic, and mercury being added. In many cases, the toxicities of the starting materials for synthesizing coloring agents were well known and could be toxins, irritants, sensitizers, or carcinogens. 
To determine how much dye is safe to use, toxicologists take the highest dose that did not cause any adverse effect in animal tests and divide it by 100. The resulting number is the Acceptable Daily Intake (ADI)—the amount any human can ingest every day for a lifetime without experiencing problems. Most foods containing dyes have only a tiny fraction of the ADI.

Risks include hyperactivity in children, cancer (in animal studies), and allergic reactions. In 2008, because of the problem of hyperactivity, the Center for Science in the Public Interest petitioned the Food and Drug Administration to ban the use of these dyes. The British government has taken actions that are virtually ending the use of dyes throughout Europe.


Current Seven Food Dyes 

Blue No.1- Brilliant Blue
 
Blue No. 2- Indigotine
File:Indigo carmine.svg
Green No. 3- Fast Green 
Red No. 40- Allura Red
File:Allura Red AC Formula V.1.svg
Red No. 3- Erythosine
Yellow No. 5- Tartazine
Yellow No. 6- Sunset Yellow






http://www.cspinet.org/fooddyes/
http://www.fda.gov/Forindustry/ColorAdditives/default.htm


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